老年急性髓样白血病的治疗进展

doi:10.3969/j.issn.1004-583X.2023.10.018

摘要/Abstract

摘要：

急性髓样白血病(acute myeloid leukemia, AML)是一种血液系统恶性疾病,其特征是髓系前体的克隆性扩增,在参与自我更新、增殖和分化的过程中获得遗传异常。AML在老年群体中发病率更高, 预后更差。目前,对于AML发病机制的研究取得了长足进展,但由于老年患者对化疗耐受力差,治疗选择常受限。近年来,针对AML的新疗法逐渐被开发,老年AML的治疗方案逐渐增多,包括对细胞毒性化学疗法、表观遗传靶向药物以及免疫疗法等。同时,不同作用机制药物的联合应用也不断被探索,老年AML患者的治疗及预后有望得到改善。

中图分类号:

R733.72

陈璨, 黄永芬, 苗雨青. 老年急性髓样白血病的治疗进展[J]. 临床荟萃, 2023, 38(10): 954-960.

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https://huicui.hebmu.edu.cn/CN/Y2023/V38/I10/954

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老年急性髓样白血病的治疗进展

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