临床荟萃 ›› 2014, Vol. 29 ›› Issue (7): 754-757.

• 论文 • 上一篇    下一篇

局部晚期直肠癌同步放化疗前后血浆D-二聚体和高密度脂蛋白对疗效评价的意义

王欣;曹军丽;高立明;程少会;董立新;曹丽艳;付占昭   

  1. 秦皇岛市中医医院 重症医学科,河北 秦皇岛,066000%秦皇岛市第一医院 肿瘤科,河北 秦皇岛,066000
  • 出版日期:2014-07-05 发布日期:2014-07-05

Clinical significance of plasma D-dimer and high-density lipoprotein level before and after concurrent chemoradiotherapy in patients with advanced rectal cancer

WANG Xin;CAO Jun-li;GAO Li-ming;CHENG Shao-hui;DONG Li-xin;CAO Li-yan;FU Zhan-zhao   

  • Online:2014-07-05 Published:2014-07-05

摘要: 分析同步放化疗前后局部晚期直肠癌患者血浆 D-二聚体和高密度脂蛋白胆固醇(HDL-C)水平的变化在疗效评价中的意义。方法采用胶乳增强免疫比浊法和直接法测定106例局部晚期直肠癌患者同步放化疗前后血浆D-二聚体和 HDL-C水平的变化,并与96例健康体检者做对照。结果与健康体检者相比,局部晚期直肠癌患者的血浆D-二聚体水平明显升高(P<0.01),HDL-C水平明显降低(P <0.01)。同步放化疗后有效组 D-二聚体水平明显降低(P<0.01),HDL-C水平明显升高(P<0.01),差异有统计学意义。同步放化疗后无效组血浆 D-二聚体水平明显升高(P<0.05),HDL-C水平明显降低(P <0.01)。结论局部晚期直肠癌患者同步放化疗前后血浆D-二聚体和高密度脂蛋白的水平变化可为疗效评价提供依据。

关键词: 呼吸

Abstract: Objective To explore the clinical significance of plasma D-dimer and high density lipoprotein(HDL) level before and after concurrent chemoradiotherapy in patients with advanced rectal cancer.Methods The plasma D-dimer and HDL were detected in 106 patients

Key words: rectal neoplasms, D-dimer, cholesterol;HDL, chemoradiotherapy;adjuvant, comparative effectiveness research

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