临床荟萃 ›› 2015, Vol. 30 ›› Issue (1): 67-70.

• 论文 • 上一篇    下一篇

多脏器功能障碍综合征患者连续性血液滤过治疗肝素用量与病情危重程度及预后的相关性

田惠玉;姜相明;宋邵华;张杰;陆鹏;金玉洁;杨秀芬   

  1. 河北医科大学第一医院 重症医学科,河北 石家庄,050031
  • 出版日期:2015-01-05 发布日期:2015-01-05
  • 基金资助:
    河北省卫生厅医学科学研究重点课题(20100270)

Relationship between permissible dose of heparin and severity of illness and prognosis in patients with multiple organ dysfunction syndrome during continuous veno-venous hemofiltration

Tian Huiyu;Jiang Xiangming;Song Shaohua;Zhang Jie;Lu Peng;Jin Yujie;Yang Xiufen   

  • Online:2015-01-05 Published:2015-01-05

摘要: 目的:探讨多脏器功能障碍综合征(multiple organ dysfunction syndrome MODS)患者连续性血液滤过治疗肝素许可用量与预后的相关性分析。方法选择我院 MODS 行连续性血液滤过治疗患者60例,依据预后分为死亡组和存活组。评估肝素许可用量与病情危重程度及预后的相关性。结果①肝素的平均许可用量(8.27±1.19) U·kg-1·h-1。死亡组肝素的许可用量明显少于存活组,(6.55±1.48)U·kg-1·h-1 vs (9.59±0.96)U·kg-1· h-1(P <0.05)。②肝素的许可用量与年龄、APACHEⅡ评分呈明显负相关(r =-0.550,-0.563,P <0.01)。结论 MODS 患者连续性血液滤过治疗中肝素的许可用量与 MODS 患者的预后密切相关。

关键词: 肾透析, 胃肠出血, 危险因素

Abstract: ABSTRACT:Objective To investigate the relationship between permissible dose of heparin and the severity of illness and the prognosis of the patients with multiple organ dysfunction syndrome(MODS)during continuous veno-venous hemofiltration(CVVH).Methods S

Key words: multiple organ failure, hemofiltration, heparin, prognosis

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