临床荟萃 ›› 2015, Vol. 30 ›› Issue (12): 1413-1416.

• 论文 • 上一篇    下一篇

延长睡眠时间与中风风险的荟萃分析

何月;彭巧玲;周国庆   

  1. 南京军区南京总医院 干部神经内科,江苏 南京,210002
  • 出版日期:2015-12-05 发布日期:2015-12-05

A meta-analysis of relative ratio of stroke with sleep duration

He Yue;Peng Qiaoling;Zhou Guoqing   

  • Online:2015-12-05 Published:2015-12-05

摘要: 目的:分析延长睡眠时间与中风风险,对睡眠时间延长是否增加中风风险做出循证医学分析。方法检索 MEDLINE、PUBMED、EMBASE、WOS 1997~2015年相关文献,Jadad 评分评估所涉及研究的质量,剔除评分小于4分的研究,取得每项研究的睡眠时间与中风风险的相对风险度(RR )值及95%可信区间(95% CI ),STATA 11.0合并分析睡眠时间延长与中风风险的 RR 及 P 值,并通过分层(按性别、短暂延长睡眠时间、长时延长睡眠时间)进一步分析睡眠时间延长与中风的风险。结果延长睡眠时间(>8小时)中风总风险增高(RR =1.28,95% CI =1.22~1.35,P =0.00);短暂延长睡眠时间(8~10小时)中风风险增高(RR =1.15,95% CI =1.07~1.24,P =0.00);其中未分性别研究中风风险度增高(RR =1.12,95% CI =1.00~1.24,P =0.052);男性中风风险增高(RR =1.11,95% CI =0.95~1.29,P =0.198);女性中风风险增高(RR =1.24,95% CI =1.09~1.43,P =0.002)。长时间延长睡眠时间(≥10小时)中风风险增高(RR =1.41,95% CI =1.32~1.52,P =0.00);其中未分性别中风风险增高(RR =1.30,95% CI =1.17~1.45,P =0.00);男性中风风险增高(RR =1.46,95% CI =1.29~1.66,P =0.00);女性中风风险增高(RR =1.56,95% CI =1.36~1.78,P =0.00)。结论延长睡眠眠时间(>8小时)中风风险发生率明显增加。

关键词: 肾病综合征, 肾小球肾炎

Abstract: Related articles (1 997-201 5)were searched in MEDLINE,PUBMED,EMBASE and WOS.The quality of the included studies was evaluated by the Jadad scale.The relative ratio (RR)and their 95% confidence interval were pooled.RR was evaluated by meta-analysis method

Key words: stroke, sleep, meta-analysis, risk factors

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