临床荟萃 ›› 2015, Vol. 30 ›› Issue (9): 1036-1038.

• 论文 • 上一篇    下一篇

扶正补虚方对原发性肝癌患者T细胞亚群及血管生成相关因子影响

郑建晓;吴金明   

  1. 温州医科大学附属乐清医院 中西医结合科,浙江 温州,325600%温州医科大学,浙江 温州,325000
  • 出版日期:2015-09-05 发布日期:2015-09-05

Effect of Fuzhengbuxu decotion on T cell subsets and angiogenesis related factors of patients with primary hepatic carcinoma

Zheng Jianxiao;Wu Jinming   

  • Online:2015-09-05 Published:2015-09-05

摘要: 目的:探讨扶正补虚方治疗原发性肝癌治疗效果及对患者免疫功能和血管生长因子的影响。方法将86例原发性肝癌患者采用随机数字表法分为观察组与对照组,对照组给予常规化疗方案,观察组在对照组基础上联合扶正补虚方治疗,记录两组疗效。结果观察组治疗总有效率为32.6%(14/43),对照组治疗总有效率为14.0%(6/43),差异有统计学意义(P <0.05)。观察组治疗后 CD3+ T(65.98±7.83),CD4+ T(41.02±5.27),CD8+ T (21.34±2.05),CD4+ T/CD8+ T(1.59±0.84);对照组治疗后 CD3+ T(52.93±5.24),CD4+ T(31.89±4.11),CD8+T(34.85±4.59),CD4+ T/CD8+ T(1.03±0.45),差异有统计学意义(P <0.05)。观察组治疗后血管内皮生长因子(VEGF)(21.05±5.78)ng/L,基质蛋白酶9(MMP-9)(6.11±2.41)ng/L;对照组治疗后 VEGF(29.02±9.97)ng/L, MMP-9(9.63±4.01)ng/L,差异有统计学意义(P <0.05)。结论采用扶正补虚方可以提高原发性肝癌临床疗效,通过改善肝癌患者细胞免疫功能,抑制患者血清 VEGF 和 MMP-9浓度,值得在临床上推广应用。

关键词: 睡眠呼吸暂停

Abstract: Objective To explore the effect of Fuzhengbuxu decotionon on the immune function and vascular growth factors in patients with primary liver carcinoma.Methods According to random number table method,86 patients with primary werer carcinoma were divided int

Key words: liver neoplasms, strenth resist consol constit, vascular endothelial growth factor, matrix metalloproteinase 9

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