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LGI1抗体相关边缘叶脑炎1例及文献复习

  

  1. 1.南京医科大学第一附属医院 神经内科,江苏 南京 210029;2.苏州市立医院 神经内科,江苏 苏州 215000
  • 出版日期:2019-03-20 发布日期:2019-04-08
  • 通讯作者: 通信作者:程虹,Email:ch8706@hotmail.com
  • 基金资助:
    江苏省人社厅“六大人才高峰”第12批高层次人才资助项目----急性脑梗死早期外周血中的动态变化及预后评估中作用的研究(WSN-025)

LGI1 antibodyrelated limbic encephalitis: a case report and literature review

  1. 1. Department of Neurology, the First Affiliated Hospital of Nanjing Medical University,
    Nanjing  210029, China;  2. Department of Neurology, Suzhou Municipal Hospital, Suzhou 215000, China
  • Online:2019-03-20 Published:2019-04-08
  • Contact: Corresponding author:Cheng Hong,Email:ch8706@hotmail.com

摘要: LGI1抗体相关的边缘叶脑炎是以突发认知及情感变化、癫痫发作为主要特点的自身免疫性疾病,很少伴发肿瘤且对免疫治疗反应较好,及时诊断及治疗有助于患者的远期预后。报道本院收治的LGI1抗体脑炎1例。

关键词: 脑炎, 抗体, 认知障碍, 免疫治疗

Abstract: LGI1 antibody related  limbic encephalitis is an autoimmune disease characterized by sudden cognitive,  and  emotional changes and epileptic seizures. It rarely coincides with tumor and has a better response to immunotherapy. The early diagnosis and appropriate treatment suggest a better prognosis for patients. A case of LGI1 antibody related limbic encephalitis admitted to our hospital is reported.

Key words: encephalitis, antibody;cognitive impairment, immunotherapy