抗炎细胞因子在阿尔茨海默病中的研究进展

doi:10.3969/j.issn.1004-583X.2023.02.016

临床荟萃 ›› 2023, Vol. 38 ›› Issue (2): 185-188.doi: 10.3969/j.issn.1004-583X.2023.02.016

抗炎细胞因子在阿尔茨海默病中的研究进展

谢少为¹^,³, 吕小涵¹^,³, 董艳红²^,³, 吕佩源²^,³()

1.河北医科大学研究生院,河北石家庄 050017
2.河北省人民医院神经内科,河北石家庄 050051
3.河北省脑网络与认知障碍疾病重点实验室,河北石家庄 050051

收稿日期:2022-11-09 出版日期:2023-02-20 发布日期:2023-03-31
通讯作者: 吕佩源 E-mail:peiyuanlu@163.com
基金资助:
河北省自然科学基金——丁苯酞对卒中后认知障碍的治疗机制及多模影像学研究(H2022307075);河北省高端人才支持计划(冀办[2019]63号);河北省政府资助临床医学优秀人才培养项目——高分辨率磁共振成像和代谢相关指标分析在血管性认知障碍中的应用研究(冀财社[2019]139号);河北省科技创新团队——脑血管病及相关认知障碍诊疗与康复创新团队(冀政字[2020]9号)

Received:2022-11-09 Online:2023-02-20 Published:2023-03-31

摘要/Abstract

摘要：

阿尔茨海默病(Aizheimer's disease,AD)是痴呆症最常见的形式,是一种神经退行性疾病。其特征是负责控制记忆和其他认知功能的大脑区域受到损伤,神经病理是神经元丢失,淀粉样蛋白β在细胞外沉积和神经纤维缠结在细胞内积累。目前已有大量研究表明,抗炎及促炎机制在AD的病理生理中发挥着至关重要的作用。本文通过对部分抗炎细胞因子改善AD患者认知功能的机制进行综述,旨在为AD的诊疗提供新思路。

关键词: 阿尔茨海默病, 白细胞介素类, 认知障碍, 炎症

中图分类号:

R745.7

谢少为, 吕小涵, 董艳红, 吕佩源. 抗炎细胞因子在阿尔茨海默病中的研究进展[J]. 临床荟萃, 2023, 38(2): 185-188.

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链接本文: https://huicui.hebmu.edu.cn/CN/10.3969/j.issn.1004-583X.2023.02.016

https://huicui.hebmu.edu.cn/CN/Y2023/V38/I2/185

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