弥散张量成像评估帕金森病合并非运动症状患者脑微结构的研究进展

doi:10.3969/j.issn.1004-583X.2023.02.017

摘要/Abstract

摘要：

帕金森病(Parkinson's disease,PD)是中老年常见的神经退行性疾病,其发病率随年龄的增长而逐渐增高,其临床表现分为运动症状及非运动症状(non-motor symptoms,NMS)。据报道,约88%的PD患者存在NMS,包括认知功能下降、嗅觉减退,睡眠障碍,抑郁和自主神经功能障碍等。PD合并NMS可严重影响患者的生活质量,甚至发生危害生命的并发症,因此有效且可行的影像学检查对诊断疾病至关重要。弥散张量成像(diffusion tensor imaging,DTI)技术可直接反映脑白质纤维束的变化,进一步评估脑微结构的改变,为PD的诊断和治疗提供方法及证据。本文就DTI在PD合并NMS患者脑纤维束评估中的应用予以综述。

关键词: 帕金森病, 认知功能障碍, 弥散张量成像, 抑郁

中图分类号:

R742.5

王璐璐, 董露露, 江超, 王九雪, 常雅君, 王天俊. 弥散张量成像评估帕金森病合并非运动症状患者脑微结构的研究进展[J]. 临床荟萃, 2023, 38(2): 189-192.

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链接本文: https://huicui.hebmu.edu.cn/CN/10.3969/j.issn.1004-583X.2023.02.017

https://huicui.hebmu.edu.cn/CN/Y2023/V38/I2/189

参考文献 35

[1]	Usman S, Anthony EL, Mario M. Neuroimaging advances in Parkinson's disease and atypical Parkinsonian syndromes[J]. Front Neurol, 2020, 15(11):572976.
[2]	Rose BC, Liliana M, Bradford C, et al. Basal and evoked neurotransmitter levels in Parkin,DJ-1,PINK1 and LRRK2 knockout rat striatum[J]. Neuroscience, 2019, 15(409):169-179.
[3]	Onur S, Nese O, Mehmet FO. Comparison of pramipexole versus ropinirole in the treatment of Parkinson's disease[J]. Ideggyogy Sz, 2022, 75(2):39-49. doi: 10.18071/isz.75.0039 URL
[4]	Huang ST, Dong YC, Zhao JY. The mean kurtosis (MK) is more sensitive diagnostic biomarker than fractional anisotropy (FA) for Parkinson's disease: A diagnostic performance study and meta-analysis[J]. Medicine (Baltimore), 2022, 101(45):e31312. doi: 10.1097/MD.0000000000031312 URL
[5]	Silvia LP. Diffusion tensor imaging (DTI)[J]. Methods Mol Biol, 2018, 1718:103-116.
[6]	Zhang Y, Marc AB. Corrigendum: Diffusion tensor imaging in Parkinson's disease and Parkinsonian syndrome: A systematic review[J]. Front Neurol, 2020, 11:612069. doi: 10.3389/fneur.2020.612069 URL
[7]	Woo S, Byung J, Sung B, et al. Current clinical applications of diffusion-tensor imaging in neurological disorders[J]. J Clin Neurol, 2018, 14(2):129-140. doi: 10.3988/jcn.2018.14.2.129 pmid: 29504292
[8]	Hamed M, Saman S, Ebrahim K, et al. Probiotics and the treatment of Parkinson's disease: An update[J]. Cell Mol Neurobiol, 2022, 42(8):2449-2457. doi: 10.1007/s10571-021-01128-w
[9]	Tuva RH, Per S, Irena R, et al. Diffusion tensor and restriction spectrum imaging reflect different aspects of neurodegeneration in Parkinson's disease[J]. PLoS One, 2019, 14(5):0217922.
[10]	Shang SA, Li DX, Tian YY, et al. Hybrid PET-MRI for early detection of dopaminergic dysfunction and microstructural degradation involved in Parkinson's disease[J]. Commun Biol, 2021, 4(1):1162. doi: 10.1038/s42003-021-02705-x pmid: 34621005
[11]	Domínguez-Chávez CJ, Murrock CJ, Salazar-González BC. Mild cognitive impairment: A concept analysis[J]. Nurs Forum, 2019, 54(1):68-76. doi: 10.1111/nuf.12299 pmid: 30261109
[12]	Jennifer G, Erica S. Cognitive impairment and dementia in Parkinson disease[J]. Clin Geriatr Med, 2020, 36(2):365-377. doi: S0749-0690(20)30001-X pmid: 32222308
[13]	高亚军, 刘峰, 高晓嵘. 脑白质微结构改变与帕金森病认知功能损害的相关性[J]. 陕西医学杂志, 2016, 45(4):448-449.
[14]	Matsui H, Nishinaka K, Oda M, et al. Dementia in Parkinson's disease: Diffusion tensor imaging[J]. Acta Neurol Scand, 2007, 116(3):177-181. doi: 10.1111/j.1600-0404.2007.00838.x pmid: 17714331
[15]	Wang WY, Mei MJ, Gao YY, et al. Changes of brain structural network connection in Parkinson's disease patients with mild cognitive dysfunction: A study based on diffusion tensor imaging[J]. J Neurol, 2020, 267(4):933-943. doi: 10.1007/s00415-019-09645-x pmid: 31792673
[16]	Sebastiano G, Federica A, Elka S, et al. Structural brain connectome and cognitive impairment in Parkinson disease[J]. Radiology, 2017, 283(2):515-525. doi: 10.1148/radiol.2016160274 pmid: 27924721
[17]	Thais M, Li S, Elijah M, et al. Longitudinal diffusion tensor imaging changes in early Parkinson's disease: ICICLE-PD study[J]. J Neurol, 2018, 265(7):1528-1539. doi: 10.1007/s00415-018-8873-0 pmid: 29696499
[18]	Naroa I, Carme J, Maria-Jose M, et al. Olfactory impairment in Parkinson's disease and white matter abnormalities in central olfactory areas: A voxel-based diffusion tensor imaging study[J]. Mov Disord, 2010, 25(12):1888-1894. doi: 10.1002/mds.23208 URL
[19]	梁红红. 帕金森病伴嗅觉障碍患者的弥散张量成像研究[D]. 郑州: 郑州大学, 2019.
[20]	Nigro P, Chiappiniello A, Simoni S, et al. Changes of olfactory tract in Parkinson's disease: A DTI tractography study[J]. Neuroradiology, 2021, 63(2):235-242. doi: 10.1007/s00234-020-02551-4
[21]	Hossein S, Mahsa D, Elaheh S, et al. Association of olfaction dysfunction with brain microstructure in prodromal Parkinson disease[J]. Neurol Sci, 2019, 40(2):283-291. doi: 10.1007/s10072-018-3629-2 pmid: 30386933
[22]	Zhang KY, Yu CS, Zhang YJ, et al. Voxel-based analysis of diffusion tensor indices in the brain in patients with Parkinson's disease[J]. Eur J Radiol, 2011, 77(2):269-273. doi: 10.1016/j.ejrad.2009.07.032 pmid: 19692193
[23]	Charalampos G, Marcel W, Nil D, et al. Olfactory impairment in Parkinson's disease studied with diffusion tensor and magnetization transfer imaging[J]. J Parkinsons Dis, 2017, 7(2):301-311.
[24]	Joshi N, Rolheiser TM, Fisk JD, et al. Lateralized microstructural changes in early-stage Parkinson's disease in anterior olfactory structures,but not in substantia nigra[J]. J Neurol, 2017, 264(7):1497-1505. doi: 10.1007/s00415-017-8555-3 pmid: 28653210
[25]	Li ZH, Liu WG, Xiao CY, et al. Abnormal white matter microstructures in Parkinson's disease and comorbid depression: A whole-brain diffusion tensor imaging study[J]. Neurosci Lett, 2020, 735(1):135238. doi: 10.1016/j.neulet.2020.135238 URL
[26]	Osamu A, Hidenori Y, Kiyoto K, et al. Voxel-based analyses of gray/white matter volume and diffusion tensor data in major depression[J]. Psychiatry Res, 2010, 181(1):64-70. doi: 10.1016/j.pscychresns.2009.07.007 URL
[27]	Ning HX, Zhou H, Ren JR, et al. Zishen pingchan granules combined with pramipexole in the improvement of depressive symptoms in Parkinson's disease: A prospective, multicenter, randomized, double-blind, controlled clinical study[J]. J Transl Med, 2022, 20(1):357. doi: 10.1186/s12967-022-03551-z pmid: 35962349
[28]	Stéphanie M, Eric J, Isabelle Klein. Cognitive dysfunction and brain atrophy in Susac syndrome[J]. J Neurol, 2020, 267(4):994-1003. doi: 10.1007/s00415-019-09664-8 pmid: 31828475
[29]	Hu Xi, Qian L, Zhang Y, et al. Topological changes in white matter connectivity network in patients with Parkinson's disease and depression[J]. Brain Imaging Behav, 2020, 14(6):2559-2568. doi: 10.1007/s11682-019-00208-2
[30]	Ambra S, Birgit H. Sleep in Parkinson's disease[J]. Neuropsychopharmacology, 2020, 45(1):121-128. doi: 10.1038/s41386-019-0448-y pmid: 31234200
[31]	Andrew HF, Gordon WD, Michael JF, et al. Rapid eye movement sleep behavior disorder in Parkinson's disease: Magnetic resonance imaging study[J]. Mov Disord, 2013, 28(6):832-836. doi: 10.1002/mds.25367 URL
[32]	Lim JS, Shin SA, Lee JY, et al. Neural substrates of rapid eye movement sleep behavior disorder in Parkinson's disease[J]. Parkinsonism Relat Disord, 2016, 23(2):31-36. doi: 10.1016/j.parkreldis.2015.11.027 URL
[33]	Lisa O, Colette MS, Jodie RG. Tract-based spatial statistics reveal lower white matter integrity specific to idiopathic rapid eye movement sleep behavior disorder as a proxy for prodromal Parkinson's disease[J]. J Parkinsons Dis, 2019, 9(4):723-731.
[34]	Rafail M, Kuangyu S, Artemios A, et al. Brain neuroimaging of rapid eye movement sleep behavior disorder in Parkinson's disease: A systematic review[J]. J Parkinsons Dis, 2022, 12(1):69-83.
[35]	Zhou LC, Li GL, Zhang YY, et al. Increased free water in the substantia nigra in idiopathic REM sleep behaviour disorder[J]. Brain, 2021, 144(5):1488-1497. doi: 10.1093/brain/awab039 pmid: 33880500

弥散张量成像评估帕金森病合并非运动症状患者脑微结构的研究进展

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