关键词: 关节炎,  , 类风湿, 磁共振成像, 抗环瓜氨酸多肽抗体, 类风湿因子

Abstract: Objective  To investigate the correlation between semiquantitative MRI microcoil and antiCCP antibody and rheumatoid factor(RF) level in rheumatoid arthritis（RA）.Methods  A total of 80 RA patients treated in our hospital from June 2018 to March 2019 were enrolled. MRI microcoil plain scan and enhanced scan were performed on all patients. Synovial score was graded by semiquantitative method. Serum RF and antiCCP antibody levels were collected to analyze the correlation between synovial score and serum factors. Results  Totally 15 cases were tested positive by Xray plain film,  with a positive rate of  18.75%,  while the positive rate of MRI microcoil image was 100%. The positive rate of MRI microcoil was significantly higher than that of Xray (χ2=109.474,  P=0.000);  80 patients with early RA showed different degrees of synovial thickening; the levels of serum RF and antiCCP antibody of RA patients in bone erosion group were significantly higher than those of RA patients in normal bone group(P<0.05); the total score of synovium was positively correlated with serum RF(r=0.561, P=0.000) and antiCCP antibody (r=0.631, P=0.000). Conclusion  MRI microcoil semiquantitative method can effectively evaluate the situation of early RA synovitis,  and the synovial score is positively correlated with serum RF and antiCCP antibody,  which has a certain value for early diagnosis of RA.

Key words: arthritis, , rheumatoid ；magnetic resonance imaging, semiquantitative; , anticyclic citrullinated peptide antibody, rheumatoid factor