临床荟萃 ›› 2023, Vol. 38 ›› Issue (7): 663-667.doi: 10.3969/j.issn.1004-583X.2023.07.014
收稿日期:
2023-05-14
出版日期:
2023-07-20
发布日期:
2023-09-01
通讯作者:
崔轶霞
E-mail:yixia_cyx@126.com
Received:
2023-05-14
Online:
2023-07-20
Published:
2023-09-01
摘要:
随着生物-心理-社会医学模式的广泛推行,心理社会因素在躯体疾病的作用日益显著。类风湿关节炎(rhematoid arthritis,RA)是一种侵蚀关节滑膜的慢性炎症,此病有起病急、进展迅速、病程迁延不愈等特点,患者生理、心理长期受到不良影响,极易并发抑郁症。随着各项研究的深入,RA释放的炎症因子、下丘脑-垂体-肾上腺轴的激素等也影响着患者的抑郁状况,然而,抑郁症能激发免疫因子与炎症因子的释放,对RA的疾病活动度、疼痛程度有不同程度的影响,进一步加重抑郁症状,影响预后。评估患者抑郁状况及对抑郁症合理的治疗,有助于延缓RA的疾病进展及预后。
中图分类号:
孙佳宁, 崔轶霞. 类风湿关节炎与抑郁症共病的研究进展[J]. 临床荟萃, 2023, 38(7): 663-667.
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