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兰州市城关区居民甲状腺结节与碘营养状况调查

  

  1. 1. 兰州大学第一医院  内分泌科,甘肃  兰州  730000;2. 中国医科大学附属第一医院  内分泌科,辽宁  沈阳  101100
  • 出版日期:2018-07-05 发布日期:2018-08-06
  • 通讯作者: 通信作者:傅松波,Email:fusb@lzu.edu.cn
  • 基金资助:
    国家卫计委公益性行业科研专项(201402005);兰州市城关区科技计划项目(2014-7-4);兰州大学2017年大学生创新创业项目行动计划(20171073001237)

Survey of thyroid nodules and iodine nutritional status of residents in Chengguan District of Lanzhou

  1. 1.Department of Endocrinology, the First Hospital of Lanzhou University, Lanzhou 730000, China;
    2. Department of Endocrinology, the First Affiliated Hospital of China Medical University,
    Shenyang 101100, China
  • Online:2018-07-05 Published:2018-08-06
  • Contact: Corresponding author: Fu Songbo, Email: fusb@lzu.edu.cn

摘要: 目的  了解兰州市城关区居民碘营养状况和甲状腺结节的流行病学特征及影响因素。方法  采用分层整群抽样的方法对兰州市城关区6个社区进行横断面调查,进行甲状腺超声检查、甲状腺功能检测及尿碘检测。结果  甲状腺结节的患病率为21.0%,男、女分别为17.2%、25.2%,女性高于男性(P<0.05)。60岁之前患者人群以单发和直径<1.0  cm的结节为主,60岁之后以多发和直径≥1.0  cm的结节为主。甲状腺结节患者的甲状腺功能多为正常(81.6%),且二者无关联(P>0.05)。兰州地区人群尿碘中位数为205.4  μg/L,高于国内其他地区,女性高于男性(P<0.05),尿碘水平随着年龄升高而逐渐降低(P<0.05)。年龄是甲状腺结节发生与发展的重要影响因素。结论  兰州地区的尿碘水平较高;年龄与性别均与甲状腺结节的发生发展有关。

关键词: 甲状腺结节, 碘, 甲状腺功能试验

Abstract: Objective  To understand the iodine nutritional status in Chengguan District of Lanzhou, and the epidemiological characteristics and influencing factors of thyroid nodules. Methods  Stratified cluster sampling was used to conduct a crosssectional survey on six communities. Thyroid ultrasound, thyroid function and urine iodine were tested. Results  The prevalence rate of thyroid nodules was 21.0% as a whole, with that of the men being, 17.2% and that of women being. Obviously, the prevalence rate of. women was higher than men (P<0.05).The majority of patients under 60 years had single nodules less than 1.0  cm. Patients over 60 years had multiple thyroid nodules with the diameter greater than or equal to 1.0  cm. Thyroid function in patients with thyroid nodules was normal (81.6%), and there was no association between thyroid nodules and thyroid function(P>0.05). The median urinary iodine level in Lanzhou area was 205.4  μg/L, higher than that in other areas of China, and significantly higher in women than men (P<0.05). The urine iodine level decreased with age (P<0.05). Age is an important factor affecting the occurrence and development of thyroid nodules. Conclusion  The level of urine iodine is high in Lanzhou area. Both age and sex are related to the occurrence and development of thyroid nodules.

Key words: thyroid nodule, iodine, thyroid function tests