长链非编码RNA与冠心病相关性研究进展

doi:10.3969/j.issn.1004-583X.2021.05.015

摘要/Abstract

摘要：

长链非编码RNA(long non-coding RNA, lncRNA)能够调控基因表达, 有望成为冠心病患者的治疗选择之一。并且大量研究证明lncRNA在冠心病及其亚型中发挥重要作用, lncRNA被认为是新的功能调控分子参与到动脉粥样硬化、冠心病、心肌梗死、心力衰竭、心绞痛和冠状动脉慢性完全闭塞等疾病的发生发展中。其中一些lncRNA还具有成为诊断标志物的潜力。本文旨在从lncRNA的生物学特点以及在冠心病进展中的分子机制进行综述。

关键词: RNA, 长链非编码, 冠状动脉疾病, 心肌梗死

中图分类号:

R541.4

尹亮, 刘德敏, 谷国强. 长链非编码RNA与冠心病相关性研究进展[J]. 临床荟萃, 2021, 36(5): 462-466.

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链接本文: https://huicui.hebmu.edu.cn/CN/10.3969/j.issn.1004-583X.2021.05.015

https://huicui.hebmu.edu.cn/CN/Y2021/V36/I5/462

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长链非编码RNA与冠心病相关性研究进展

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