临床荟萃 ›› 2022, Vol. 37 ›› Issue (4): 364-368.doi: 10.3969/j.issn.1004-583X.2022.04.015
吴天娇1, 常璐1, 李梓浩1, 徐丹2, 尹昌浩2, 赵维纳2(
)
收稿日期:2021-11-22
出版日期:2022-04-20
发布日期:2022-05-13
通讯作者:
赵维纳
E-mail:zhaoweina@mdjmu.edu.cn
基金资助:
Received:2021-11-22
Online:2022-04-20
Published:2022-05-13
摘要：
血管性认知障碍(vascular cognitive impairment,VCI)是由脑血管病导致的不同程度的认知功能损害,包括注意力、记忆力、执行力的下降,并且会影响患者的日常生活,但其发病机制尚未明确。微RNA(microRNA, miRNA)是一类短链非编码RNA,在调节各种神经系统疾病中起重要作用。但是,miRNA在VCI发病机制中的作用尚未得到很好的阐明。本文将主要从血脑屏障、突触可塑性、炎症和神经元自噬等方面对miRNA在VCI发病机制中的最新研究进展进行综述。
中图分类号:
吴天娇, 常璐, 李梓浩, 徐丹, 尹昌浩, 赵维纳. 微RNA在血管性认知障碍发病机制中的研究进展[J]. 临床荟萃, 2022, 37(4): 364-368.
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