Diagnosis and treatment of subclinical hypothyroidism in pregnancy

doi:10.3969/j.issn.1004-583X.2016.03.009

Abstract

Abstract: Subclinical hypothyroidism(SCH) is defined as elevated serum thyrotropin (TSH) level with a normal serum-free thyroxine (FT4) level.Gestational age-specific criteria should be used for the diagnosis of SCH. Pregnant women with SCH,especialy those with higher thyroid autoantibody levels, have increased risks of adverse maternal outcomes, perinatal complications and their offsprings have increased risks of mental and physical disorders. Routine maternal thyroid function tests including FT4,TSH and TPOAb are necessary to improve maternal and perinatal outcomes. The best time for the screening is within eight weeks of pregnancy. Women with SCH whether before or during pregnancy should be treated with oral levothyroxine. TSH levels should be maintained within pregnancy specific reference range. Adequate iodine supplementation during pregnancy is critical and if feasible it should be initiated before the woman attempts to conceive. The extra 150 μg daily supplement is recommended and potassium iodide is the best choice.

Key words: acuteatrialfibrillation, hemodynamic, treatmentplan, hypothyroidism, pregnancy, screening, treatment

CLC Number:

R581.2

Zhang Songyun. Diagnosis and treatment of subclinical hypothyroidism in pregnancy[J]. Clinical Focus, 2016, 31(3): 268-271.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2016.03.009

https://huicui.hebmu.edu.cn/EN/Y2016/V31/I3/268

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