Abstract:

Objective  To investigate the incidence of cognitive impairment and its correlation with uric acid in elderly patients with cerebral infarction. Methods  A total of 102 elderly patients with cerebral infarction were selected in clinical practice. Based on the MoCA, all patients were divided into two groups: cognitive impairment group and normal cognitive group. Differences in the uric acid and other related factors were compared between two groups, and logistic regression analysis was used to estimate the correlation between uric acid and cognitive impairment. Results   The incidence of cognitive impairment among all 102 patients was 58.8% (60 cases). Serum uric acid was significantly higher in cognitive impairment group than in normal group (P＜0.01). The multiple logistic regression analysis showed that high uric acid was associated with cognitive impairment (OR=1.043, 95%CI  1.0201.067,P＜0.01). Conclusion   The incidence of cognitive impairment in elderly patients with cerebral infarction was higher, and uric acid was considered  the risk factor of cognitive impairment in elderly patients with cerebral infarction.

Key words: brain infarction, cognition disorders, uric acid