Clinical characteristics and risk factors in type 2 diabetic nephropathy

doi:10.3969/j.issn.1004-583X.2017.09.007

Abstract

Abstract: Objective To investigate the clinical characteristics and risk factors in type 2 diabetic nephropathy. Methods A total of 3 251 type 2 diabetes mellitus patients were chosen to carry on a retrospective casecontrol study.According to nephropathy or not，the patients were divided into DN group and nonDN group，general information and laboratory examination were compared between. The related risk factors of type 2 diabetic nephropathy were analyzed by logistic regression.Results Disease course，body mass index(BMI)，systolic blood pressure(SBP)，diasstolic blood pressure(DBP)，total cholesterol(TC)， triglyceride(TG)，low density lipoprotein cholesterol(LDLC)，creatinine(Cr)，serum uric acid(SUA)，fasting blood glucose(FPG)，hemoglobin A1c(HbA1c)， fibrinogen in DN group were significantly higher than those of nonDN group (P<0.05).Logistic regression analysis showed that disease course two groups， smoking， BMI，SBP， SUA， HbAlc and TG were risk factors of type 2 diabetic nephropathy.Conclusion The risk factors of type 2 diabetic nephropathy are disease course， smoking， BMI，SBP， SUA， HbAlc and TG， early screening for highrisk factors are recommended to reduce the occurrence of type 2 diabetic nephropathy.

Key words: diabetes mellitus, type 2, diabetic nephropathy, risk factors

Luo Jiakai， Li Zhihong， Yin Fei， Yuan Xiaochao， Wang Xin. Clinical characteristics and risk factors in type 2 diabetic nephropathy[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2017.09.007.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2017.09.007

https://huicui.hebmu.edu.cn/EN/Y2017/V32/I9/763

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Clinical characteristics and risk factors in type 2 diabetic nephropathy

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