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Research progress on antiplatelet therapy in special populations of acute coronary syndrome

  

  1. Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang  050000, China
  • Online:2018-09-05 Published:2018-09-26
  • Contact: Corresponding author: Wang Mei, Email: wangmei86632@sina.com

Abstract: Antiplatelet therapy is the cornerstone of the treatment for patients with acute coronary syndrome (ACS), and aspirin combined with a P2Y12 receptor inhibitor is currently the I recommendation in the guidelines. Antiplatelet therapy increases the risk of bleeding while reducing major cardiovascular adverse events in ACS patients. Therefore, for some special populations such as advanced age, diabetes, stroke/TIA,  and STEMI patients receiving thrombolysis, the antiplatelet therapy regimen and duration are presenting huge individual differences while evaluating the ischemia risk and bleeding risk. This article reviews the current research progress of antiplatelet therapy in these special populations.

Key words: acute coronary syndrome, anticoagulants, myocardial infarction;aged