Clinical Focus ›› 2021, Vol. 36 ›› Issue (10): 874-879.doi: 10.3969/j.issn.1004-583X.2021.10.002

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The standard treatment of acute lymphoblastic leukemia

Lu Wenyi, Zhao Mingfeng()   

  1. Department of Hematology, Tianjin First Central Hospital, First Affiliated Central Hospital of Nankai University, Tianjin Medical Key Construction Subject Internal Medicine (Hematology), Tianjin 300192, China
  • Received:2021-06-29 Online:2021-10-20 Published:2021-11-10
  • Contact: Zhao Mingfeng E-mail:mingfengzhao@sina.com

Abstract:

Acute lymphoblastic leukemia(ALL) is a highly heterogeneous hematological malignancy resulting from clonal proliferation of lymphoid precursor cells. In recent years, with the optimization of risk stratification model and the emergence of new drugs, such as tyrosine kinase inhibitors, monoclonal antibodies, chimeric antigen receptor T cells and other targeted drugs, the outcomes of ALL patients have been greatly improved. This article briefly described the current standards for treatment of ALL. Also, the latest progress in the therapy of ALL were discussed.

Key words: leukemia, lymphoid tissue, molecular targeted therapy, antibodies,monoclonal

CLC Number: