临床荟萃

• 论著 • 上一篇    下一篇

以精神症状及情感障碍起病的急性胼胝体梗死7例并文献分析

  

  1. 北京积水潭医院 神经内科,北京 100096
  • 出版日期:2016-07-05 发布日期:2016-07-08
  • 通讯作者: 通信作者:胡洪涛,Email:hhtsd@163.com

Psychiatric and affective symptoms in patients with corpus callosum infarction: seven case reports and review of literature

  1. Department of Neurology, Beijing Jishuitan Hospital, Beijing 100096, China
  • Online:2016-07-05 Published:2016-07-08
  • Contact: Corresponding author: Hu Hongtao,Email:hhtsd@163.com

摘要: 目的分析以精神症状和情感障碍起病的急性胼胝体梗死患者的临床及影像学特点,以利于患者的早期诊断和及时治疗,提高患者的预后。方法总结在我院诊治的以精神及情感障碍起病的急性胼胝体梗死患者,采用神经精神量表完全版、汉密尔顿焦虑量表和汉密尔顿抑郁量表评估患者的精神症状和情感障碍。所有患者均行头颅核磁共振检查以明确诊断和胼胝体梗死的具体部位。结果包括男性4例,女性3例,发病年龄36~75岁,平均(61.0±9.1)岁。梗死部位:膝部2例,膝部+体部2例,体部2例,体部+压部1例。迷乱的动作行为3例;易激惹及去抑制4例;激越2例,妄想2例,幻觉1例。结论对急性出现精神症状和情感障碍的患者,尤其是伴有脑血管病危险因素的患者,应考虑急性胼胝体梗死的可能,及早行头颅核磁共振检查,以免延误治疗时机。

关键词: 脑梗死, 胼胝体, 精神症状, 情感障碍

Abstract: Objective  To investigate the clinical and neuroimaging features in patients with corpus callosum infarction who presented psychiatric and affective symptoms. Methods Patients with corpus callosum infarction were examined with neuropsychiatric inventory, hamilton anxiety scale and hamilton depression rating scale for depression. All patients were performed with cranial magnetic resonance imaging.Results The study included seven patients who presented psychiatric and affective symptoms. The infarction location of two patients lied in the genu part of corpus callosum, two patients in the genu and body parts of corpus callosum, two patients in the body part of corpus callosum and one patient in the body and splenium of corpus callosum. Three patients showed abnormal behaviors, four patients showed irritability, two patients showed agitation, two patients showed delusion and one patient showed hallucination. Conclusion Corpus callosum infarction should be taken into consideration in patients with risk factors of cerebral vascular diseases who presented acute psychiatric and affective symptoms, cranial magnetic resonance imaging should be early performed to avoid delay in treatment.

Key words: brain , infarction, corpus callosum, psychiatri, affective symptoms