临床荟萃

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重视炎症性肠病的皮肤表现

  

  1. 北京大学第一医院 消化内科,北京 100034
  • 出版日期:2016-08-05 发布日期:2016-07-30
  • 通讯作者: 通信作者:李俊霞,Email:lijxtom@foxmail.com
  • 作者简介:李俊霞,北京大学第一医院消化内科副教授,副主任医师,硕士生导师。主要研究方向为炎症性肠病发病机制及临床诊疗,肠易激综合征结肠平滑肌运动及调节机制,主要研究平滑肌细胞收缩与钙稳态失衡的关系。中华医学会消化分会炎症性肠病学组成员。北京大学医学部全科医学系全科医学专业硕士研究生导师。

Clinical skin manifestations in patients with inflammatory bowel disease

  1. Department of Gastroenterology, Peking University First Hospital, Beijing  100034, China
  • Online:2016-08-05 Published:2016-07-30
  • Contact: Corrsponding author: Li Junxia,Email: lijxtom@foxmail.com

摘要: 炎症性肠病(inflammatory bowel disease, IBD)患者皮肤表现类型多样,包括炎症累及皮肤的IBD特异性皮肤表现及反应性皮肤表现;与IBD并发的皮肤表现,以及继发于其他原因而出现的IBD继发性皮肤表现。溃疡性结肠炎(ulcerative colitis, UC)患者以结节性红斑、坏疽性脓皮病为多见;克罗恩病(Crohn's disease, CD)患者以皮肤的脓肿和瘘管多见。IBD皮肤表现可以出现在IBD诊断之前、之后或同时,部分特殊类型皮肤表现的出现对IBD诊断具有提示意义。IBD皮肤损害的治疗应以控制IBD病情为基础,根据皮肤损害的类型针对性治疗。

关键词: 炎性肠疾病, 皮肤表现, 结节性红斑, 坏疽性脓皮病, 皮肤瘘管

Abstract: The types of skin manifestations in inflammatory bowel disease(IBD) patients include IBD specific skin manifestations,reactive skin manifestations,  the skin manifestations complicated  with  IBD and secondary skin manifestations of IBD related with other causes.Erythema nodosum and  pyoderma gangrenosum associated with IBD are commonly seen in ulcerative colitis,and skin abscesses and fistulas in Crohn disease. Some skin lesions may occur consequently,simultaneously or even before IBD diagnosis. Some skin lesions may indicate the development of IBD. The activity of IBD might have positive correlation with skin manifestations.Treatment of IBD skin lesions should be based on the control of IBD .Special therapy should be given according to the type of skin lesions.

Key words: inflammatory bowel diseases, skin manifestations; , erythema nodosum, pyoderma gangrenosum, fistula