临床荟萃

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幽门螺杆菌与炎症性肠病

  

  1. 河北医科大学第二医院  消化内科,河北省消化病重点实验室,河北省消化病研究所,河北  石家庄 050000
  • 出版日期:2016-08-05 发布日期:2016-07-30
  • 通讯作者: 通信作者:霍晓霞,Email: xiaoxiahuo@163.com
  • 作者简介:霍晓霞,女,河北医科大学第二医院消化内科副主任医师,医学硕士。河北省医学会消化病学分会秘书;河北省医学会消化病学分会炎症性肠病学组秘书;河北省医学会消化内镜学分会消化道早癌诊断与治疗学组委员;石家庄市医学会肝病专业委员会委员;石家庄市内镜质量管理与控制中心委员。先后参与河北省自然科学基金2项,获石家庄市科学技术进步奖三等奖2项。在专业刊物上发表论文、综述20余篇。主编、参编著作4部。

Helicobacter pylori infection and  inflammatory bowel  disease

  1. Department of Gastroenterology, the Second Hospital of Hebei Medical University,
    Hebei Key Laboratory of Gastroenterology,Hebei Institute of Gastroenterology, Shijiazhuang  050000,China
  • Online:2016-08-05 Published:2016-07-30
  • Contact: Corrsponding author: Huo Xiaoxia,Email: xiaoxiahuo@163.com

摘要: 近年来,炎症性肠病(inflammatory bowel disease, IBD)的发病率呈逐年上升趋势,但其病因尚不十分清楚,目前认为与遗传、免疫、感染及环境等多种因素密切相关。幽门螺杆菌(H.pylori)是胃内一种常见的革兰阴性微需氧菌,与消化性溃疡及消化道肿瘤密切相关。H.pylori与IBD是否存在相关性尚无定论。本文就H.pylori与IBD的关系进行综述,以期对IBD病因有更加深入的了解,也为临床治疗IBD提供新的思路。

关键词: 炎性肠疾病, 幽门螺杆菌, 临床方案

Abstract: In recent years,with a rising trend in the incidence of inflammatory bowel disease(IBD) the pathogenesis of IBD is still clear. It may associate with heredity, immunity, infection and environmental factors. Helicobacter pylori (H.pylori) is a common gramnegative micro aerobic bacteria in the stomach, which is related to peptic ulcer and gastric malignancies. A correlation between IBD and H.pylori, is uncertain. This article reviews the relationship between IBD and H.pylori in order to have a thorough understanding of the etiology of IBD, and provides a new way of thinking for the clinical treatment of IBD and H.pylori.

Key words: inflammatory bowel diseases, helicobacter pylori, clinical protocols, immunity