临床荟萃

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肾活检在糖尿病肾脏疾病诊断中的价值

  

  1. 河北医科大学第二医院 肾内科,河北 石家庄 050000
  • 出版日期:2018-10-05 发布日期:2018-11-12
  • 通讯作者: 通信作者:李绍梅,Email: lishaomeitougao@126.com
  • 作者简介:李绍梅,女,主任医师、教授、硕士研究生导师,现任河北医科大学第二医院肾内科主任。河北省医学会肾脏病学分会副主任委员,中国医师协会肾脏内科医师分会委员,石家庄市医学会肾脏病学分会常务委员,河北省血液净化质量控制委员会常务委员。从事临床、科研和教学工作。尤其在腹膜透析临床诊疗方面具有较深造诣。先后承担河北省科技厅、省卫计委课题3项,政府资助省级优秀人才项目1项,在国内核心期刊发表论文60余篇。主编学术专著4部。

Renal biopsy in diagnosis of diabetic kidney disease

  1. Department of Nephrology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
  • Online:2018-10-05 Published:2018-11-12
  • Contact: Corresponding author: Li Shaomei, Email: lishaomeitougao@126.com

摘要: 糖尿病合并肾脏疾病的肾脏病理表现复杂,非糖尿病肾病并不少见,其与糖尿病肾脏疾病(diabetic kidney disease,DKD)的治疗与预后有较大差异,早期明确诊断意义重大。单纯依靠临床表现及生化指标来诊断肾脏病变及判断预后存在较大的局限性,而近年来研究较多的用于早期诊断的新型生物标志物应用价值尚有待研究。肾活检作为一种相对安全的操作,被推荐应用于DKD的诊断、鉴别诊断、制定治疗方案和预后评估。

关键词: 糖尿病肾病, 活组织检查, 病理学

Abstract: Renal pathological manifestations of diabetic nephropathy are complicated, and nondiabetic nephropathy is not uncommon. It is quite different from the treatment and prognosis of diabetic kidney disease, and early diagnosis is of great significance.Solely relying on clinical manifestations and biochemical indicators to diagnose renal lesions and prognosis exists great limitations. Renal biopsy, as a relatively safe procedure, Compared with the new biomarkers which remains to be studied, renal biopsy,  as a relatively safe procedure, is recommended for the diagnosis, differential diagnosis,  treatment planning and prognosis evaluation of diabetic kidney disease.

Key words: diabetic nephropathy, , biopsy, pathology