临床荟萃 ›› 2021, Vol. 36 ›› Issue (8): 765-768.doi: 10.3969/j.issn.1004-583X.2021.08.019
• 综述 • 上一篇
收稿日期:
2021-06-01
出版日期:
2021-08-20
发布日期:
2021-08-30
通讯作者:
王学红
E-mail:Lindawang0710@hotmail.com
基金资助:
Received:
2021-06-01
Online:
2021-08-20
Published:
2021-08-30
摘要:
微小RNA(microRNA,miRNA)是一类常见的非编码RNA,一般不被翻译为蛋白质,其主要作用是对基因表达进行调控。miRNA种类众多,作用机制十分复杂,其中miR-146b是一类多功能的miRNA,研究发现其在恶性胶质瘤、甲状腺癌、肺癌、肝细胞癌、胰腺癌、结直肠癌等诸多恶性肿瘤中的表达水平常常发生变化。本文就miR-146b的 结构、主要作用机制以及在上述恶性肿瘤中的研究进展做一综述。
中图分类号:
陶嘉楠, 王学红, 张宏琳. miR-146b在恶性肿瘤中的研究进展[J]. 临床荟萃, 2021, 36(8): 765-768.
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