Abstract: Objective  To investigate the prevalence of diabetes mellitus among residents in Lanzhou and the related factors affecting diabetes mellitus.Methods  1 525 citizens in Lanzhou city were randomly selected as the research objects,  the age,  smoking history,  family history and history of diabetes were investigated.  Measurement included the height,  weight,  blood pressure,  waist circumference,  and static resting heart rate blood lipid,  glycosylated hemoglobin,  fasting glucose,  and blood glucose 2 hours after meal were measured.  According to the content of glycosylated hemoglobin(HbA1c),  fasting blood glucose level,  blood glucose 2 hours after meal and whether there was a history of diabetes,  the objects of study were divided into diabetes  groups,  prediabetes and diabetes glucose metabolism to normal group.  The prevalence of diabetes of Lanzhou and its risk factors were studied.Results  ①The prevalence of diabetes and prediabetes among Lanzhou residents  were  9.44% and 14.23%,  respectively.②Diabetes risk factors were age (P<0.05),  family history of diabetes (P<0.05),  weight (P<0.05),  hypertension (P<0.05),  hyperlipidemia (P<0.05). ③Age,  body mass index,  systolic blood pressure,  diastolic blood pressure,  waist circumference,  HbA1c,  plasma total cholesterol,  triglycerides,  and lowdensity lipoprotein cholesterol were significantly increased and highdensity lipoprotein cholesterol  significantly decreased in diabetic group compared with the normal glucose metabolism group(P<0.05).Conclusion  Age,  family history of diabetes,  weight,  hypertension and hyperlipidemia were risk factors for diabetes in Lanzhou.

Key words: diabetes mellitus, prevalence, factor analysis, , statistics