Abstract: Objective  To investigate the clinical characteristics of patients with pseudohypoparathyroidism(PHP) and hypokalemia. Methods  The clinical data of 13 patients with PHP in our hospital from July 2006 to April 2016 were analyzed retrospectively. Results  None of which had Albright's hereditary osteodystrophy(AHD). Convulsion  was observed in  86.4％  patients. Myasthenia and numbness of limbs were 38.5%. Hypocalcemia， hyperphospheremia and high level of parathyroid hormone was the main characteristics of laboratory examination. In all 13 cases， hypokalemia rate was 46.2%，10 with abnormal thyroid function. The course of the disease was longer in patients with hypokalemia than controls. There was no significant difference in other clinical manifestation and laboratory examination in patients with or without hypokalemia. There were no typical  AHO  body deformity. The clinical manifestations of 84.6% patients were tetany symptoms and 38.5% patients had limb weakness and numbness. 6 patients were with hypokalemia. 10 patients with abnormal thyroid function. The patients with hypokalemia had longer course of disease. The serum potassium was between 33.5  mmol/L and other clinical and biochemical indicators and non hypokalemia group had no significant difference. Conclusion  PHP patients were susceptible to hypokalemia and subclinical hypothyroidism.

Key words: pseudohypoparathyroidism；hypokalemia, hypothyroidism