Clinical Focus ›› 2021, Vol. 36 ›› Issue (10): 869-873.doi: 10.3969/j.issn.1004-583X.2021.10.001

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Standardized treatment of acute leukemia by haplo-identical stem cell transplantation

Ma Rui, Sun Yuqian()   

  1. Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematological Diseases, Beijing 100044, China
  • Received:2021-10-22 Online:2021-10-20 Published:2021-11-10
  • Contact: Sun Yuqian E-mail:sunyuqian83@hotmail.com

Abstract:

Haplo-identical stem cell transplantation(Haplo-SCT) is one of the most rapidly developing subjects in the field of transplantation in recent years. Haplo-SCT is mainly applied in more experienced centers due to the complexity of its technics. In this review, the history and current status of Haplo-SCT in treating leukemias are summarized, and the indications, donor selection, and relapse prevention/management in the “Beijing Protocol” Haplo-SCT as well as transplant strategies in special populations including elderly people are emphatically described, with the aim of providing the basis for further standardized promotion of Haplo-SCT in domestic centers.

Key words: transplantation,haploidentical, leukemia,acute

CLC Number: