Meta-analysis of risk factors for pancreatic pseudocyst in acute pancreatitis

doi:10.3969/j.issn.1004-583X.2023.04.001

Abstract

Abstract:

Objective To evaluate the risk factors of pancreatic pseudocysts in acute pancreatitis using a meta-analysis system, providing evidence based medical evidence for the prevention and treatment of pancreatic pseudocyst. Methods All relevant literature included in Medline database, Embase, Cochrane Library, web of science, CNKI, CBM, Wanfang database and VIP database from the establishment to November 2022 were first searched. The literature were then screened according to the inclusion and exclusion criteria. The Newcastle-Ottawa Scale (NOS) was used for quality evaluation. Review Manager 5.4 and Stata 14 software were applied for meta-analysis. Publication bias was evaluated by Funnel plot. Results A total of 14 articles were finally included. Meta-analysis results showed that male OR=3.94, 95%CI=(2.12-7.31), P<0.01; diabetes history OR=2.62, 95%CI=(2.04-3.36), P<0.01; CT severity index (CTSI) OR=1.5, 95%CI=(1.31-1.72), P<0.01; serum albumin level OR=0.88, 95%CI=(0.83-0.92), P<0.01; previous drinking history OR=4.36, 95%CI=(2.77-6.88), P<0.01; previous history of pancreatitis OR=2.73, 95%CI=(1.15-6.51), P<0.01; the differences were statistically significant. Conclusion Male, diabetes history, CTSI, serum albumin level, previous drinking history, and previous history of pancreatitis were associated with acute pancreatitis complicated with pancreatic pseudocyst.

Key words: pancreatitis, acute hemorrhagic, pancreatic pseudocyst, risk factors, meta-analysis

CLC Number:

R576.1

Ma Mingfu, Wei Zhiguo, He Tieying. Meta-analysis of risk factors for pancreatic pseudocyst in acute pancreatitis[J]. Clinical Focus, 2023, 38(4): 293-301.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2023.04.001

https://huicui.hebmu.edu.cn/EN/Y2023/V38/I4/293

Figures/Tables 16

References 38

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纳入研究	研究对象选择	组间可比性	暴露或结果评价	总分
范丽玉^[9]	4	2	3	9
高道键^[10]	4	1	3	8
李凡^[11]	4	2	3	9
谭蕾^[12]	4	1	3	8
徐太军^[13]	4	1	3	8
杨永明^[14]	4	1	2	7
杨子云^[15]	4	2	3	9
Maringhini^[16]	4	1	3	8
Cui^[17]	4	1	2	7
Diculescu^[18]	4	1	2	7
Kim^[19]	4	2	3	9
Poornachandra^[20]	4	1	2	7
Tan^[21]	4	2	3	9
白建平^[22]	4	1	3	8

纳入研究	研究对象选择	组间可比性	暴露或结果评价	总分
范丽玉^[9]	4	2	3	9
高道键^[10]	4	1	3	8
李凡^[11]	4	2	3	9
谭蕾^[12]	4	1	3	8
徐太军^[13]	4	1	3	8
杨永明^[14]	4	1	2	7
杨子云^[15]	4	2	3	9
Maringhini^[16]	4	1	3	8
Cui^[17]	4	1	2	7
Diculescu^[18]	4	1	2	7
Kim^[19]	4	2	3	9
Poornachandra^[20]	4	1	2	7
Tan^[21]	4	2	3	9
白建平^[22]	4	1	3	8