临床荟萃 ›› 2009, Vol. 24 ›› Issue (16): 1409-1411.

• 论文 • 上一篇    下一篇

不同剂量丙种球蛋白对急性吉兰-巴雷综合征疗效的比较

朱记军;侍海存;周桂龙   

  1. 东南大学医学院附属盐城医院神经内科,江苏,盐城,224001
  • 出版日期:2009-08-20 发布日期:2009-08-20

Comparison of low dose and high dose human gamma globulin in therapy for acute Guillian-Barre syndrome

ZHU Ji-jun;SHI Hai-cun;ZHOU Gui-long   

  • Online:2009-08-20 Published:2009-08-20

摘要: 目的 观察静脉滴注不同剂量丙种球蛋白治疗吉兰一巴雷综合征的临床疗效.方法 123倒吉兰一巴雷患者分成3组:低剂量丙种球蛋白组(0.2 g·kg-1·d-1)、大剂量丙种球蛋白组(0.4 g·kg-1·d-1)和单独应用糖皮质激素治疗组,记录其临床症状的改善状况,并进行比较.结果 低剂量和大剂量丙种球蛋白对于轻度和中度的格林一巴利患者效果好于激素组(P分别为0.004,0.008,0.012,0.022),且不良反应少,对重度患者疗效差异无统计学意义(P=0.788).低剂量和大剂量两组患者在临床疗效上没有区别.结论 丙种球蛋白治疗效果明显好于激素组,且低剂量和大剂量组差异无统计学意义.

关键词: 干燥综合征, α-胞村蛋白抗体

Abstract: Objective To observe the therapy effect of low dose and high dose human gamma globulin for acute Guillian-Barre syndrome. Methods The patients with acute Guillian-Barre syndrome were divided into three groups Improvements of clinical symptoms of human gam

Key words: Guillian-Barre syndrome, human gamma globulin, therapy

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