临床荟萃

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炎症性肠病的营养相关疾病

  

  1. 北京大学第一医院 消化科,北京 100034
  • 出版日期:2018-08-05 发布日期:2018-09-10
  • 通讯作者: 通信作者:王化虹,Email: wwwanghuahong@163.com
  • 作者简介:王化虹,主任医师,教授,博士研究生导师,消化内科主任。1982年毕业于北京医科大学。国家临床重点专科学科带头人,北京医学会消化病学分会副主委,北京医学会肠道微生态及幽门螺杆菌分会副主委,北京医师协会消化医师分会副会长,中国医疗保健国际交流促进会消化病学分会副主任委员,中国医疗保健国际交流促进会中西医结合学会常委兼炎症性肠病学组组长,中国医师协会循证医学委员会肠外肠内营养专业学组组长,中华医学会消化病学分会胃肠动力学组副组长,中央保健会诊专家,中华医学会消化病学分会炎症性肠病学组委员。中国中医药研究促进会消化整合医学分会执行常务理事、中西医结合学会北京消化分会委员、北京中西医结合学会消化学会委员,《中国中西医结合杂志》、《中华炎性肠病杂志》等编委。在Inflammatory Bowel Diseases, Case Rep Gastroenterol等国际国内杂志发表论文80余篇。出版专著10余部。培养硕士,博士生数十名。

Nutritionalrelated diseases of inflammatory bowel disease

  1. Department of Gastroenterology, Peking University First Hospital, Beijing 100034, China
  • Online:2018-08-05 Published:2018-09-10
  • Contact: Corresponding author: Wang Huahong, Email: wwwanghuahong@163.com

摘要: 炎症性肠病(IBD)中的溃疡性结肠炎和克罗恩病都属于病因不清,病情反复发作的以肠道受累为主的炎症性疾病。这样的疾病特点使得大多数患者历经数十年的病痛困扰,在漫长的病史中不论疾病的活动程度如何,甚至在疾病的缓解期营养不良的情况都是十分常见的。营养不良的情况包括蛋白质能量营养不足、超重、维生素、矿物质和微量元素的缺乏等。与IBD患者的营养不良相关的因素众多,如肠道吸收功能不良、肠道溃疡和炎症引发的营养素丢失、小肠细菌过度生长、糖皮质激素类药物的使用和饮食限制。营养支持治疗对于IBD患者至关重要,尤其是对维持儿童期IBD患者正常的生长发育、诱导活动期CD患者的临床缓解、减少IBD患者围手术期并发症等都是至关重要的。

关键词: 炎症性肠病, 营养不良, 营养和代谢性疾病

Abstract: Ulcerative colitis and Crohn disease,  which fall into the category of inflammatory bowel disease(IBD), are both chronic inflammatory diseases characterized by unclear etiology and repeated recurrence. These characteristics have caused most  of  the patients suffering from decades of trouble, and malnutrition frequentlyoccurs during theprogress of the disease,  even atthe remission period. Malnutrition includes protein energy deficiency, overweight, vitamin, mineral and trace elements deficiency. There are numerous factors associated with malnutrition in patients with IBD, such as poor intestinal absorption, loss of nutrients caused by intestinal ulcers and inflammation, excessive growth of small intestinal bacteria, use of glucocorticoids, and dietary restrictions. Nutritional support is essential for IBD patients, especially for the maintenance of normal growth and development of IBD patients in their childhood, for the treatment of CD patients at active stage, and for the reduction of perioperative complications in patients with IBD.

Key words: inflammatory bowel disease, malnutrition, nutritional and metabolic disease