Abstract: ObjectiveTo observe different vascular injuries  in diabetic patients with Htype hypertension.  MethodsA total of 379 patients with newly diagnosed T2DM were divided into three group according to whether with Htype hypertension: T2DM+Htype hypertension group (n=110)， T2DM+nonHtype hypertension group (n=110) and T2DM group (n=159). The left ventricular structure， CIMT or with carotid atherosclerotic plaque formation were tested by ultrasonic cardiogram and color flow Doppler sonography. The LVMI， UAlb/UCr and CCr were counted. Results①The levels of SBP， DBP and Hcy in T2DM+Htype hypertension group and T2DM+nonHtype hypertension group were higher than those in T2DM group， HDLC was lower than that in T2DM group. Hcy level was higher in T2DM+Htype hypertension group than in T2DM+nonHtype hypertension group， and HDLC was significantly lower (P＜0.05 or P＜0.01); ②Compared with T2DM group， the rates of LVEF＜50%， brian damage and IMT in T2DM+Htype hypertension group and T2DM+nonHtype hypertension group were significantly increased (P＜0.05 or P＜0.01)， incidence of LVH and impaired renal function in T2DM+Htype hypertension were significantly increased (P＜0.05 or P＜0.01). The levels of LVMI， UAlb/UCr and CIMT in T2DM+Htype hypertension group and T2DM+nonHtype hypertension group were significantly higher than those in T2DM group， but the LVEF was significantly lower （P＜0.05 or P＜0.01）， the levels of LVMI， CCr， UAlb/UCr and CIMT were significantly higher in T2DM+Htype hypertension group than those in T2DM+nonHtype hypertension group， and LVEF level was significantly lower (P＜0.05).  ConclusionWhen patients are newly diagnosed with diabetes， vascular injury in different parts has formed， and Htype hypertension will aggravate the damage degree.

Key words: diabetes mellitus, type 2, hypertension, hyperhomocysteinemia；vascular system injuries