Abstract: Objective To study the clinical characteristics of Chinese fulminant type 1 diabetes and understand China fulminant type 1 diabetes clinical characteristics with Japanese, Korean whether there is a difference between the two countries.Methods Analysis of clinical data of 52 patients with fulminant type 1 diabetes in China,and to study the difference between Chinese and Japanese patients.Results ①Patients with fulminant type 1 diabetes in China the average age was (32.2±12.6) years old, at least 18 years of age accounted for about 96% of the total number of patients, and the maximum number of 18 to 30 years old, about 52% of the total. ②Compared with those of Japanese patients with fulminant type 1 diabetes in our country the onset age of the lower (32.4±12.6 years vs 39.14±15.7 years,P<0.05), shorter duration (3.4±2.3 days vs 4.44±3.1 days,P<0.05), the low blood sugar (38.5±15.3 mmol/L vs 44.2±20.0 mmol/L,P<0.05); Electrolyte metabolism disorder is more serious, characterized by high potassium, low serum sodium (6.3±1.2 mmol/L vs 5.5±1.2 mmol/L,128.9±6.2 vs 131.0±9.0 mmol/L,P<0.05).③Compared with south Korean patients, the onset age of China is lower (32.4±12.6 years vs 37.4±12.4 years), and the onset of potassium is higher (6.3±1.2 mmol/L vs 5.6±1.5 mmol/L,P<0.05).Conclusion ① Fulminant type 1 diabetes is not rare in our country, and patients with adult onset. ② Compared with Japan,South Korea,the Chinese patients have the lower age of onset and higher serum potassium.

Key words: diabetes mellitus, type 1, age of onset, hyperkalemia