Analysis of related factors of diabetic peripheral neuropathy in patients with  type 2 diabetes mellitus

doi:10.3969/j.issn.1004-583X.2018.02.006

Abstract

Abstract: Objective To investigate the related factors of diabetic peripheral neuropathy in patients with type 2 diabetes mellitus(T2DM). Methods One hundred and fourteen patients with T2DM were included. Diabetic peripheral neuropathy was evaluated according to the motor and sensory nerve conduction velocity， and the patient were divided into diabetic peripheral neuropathy group (DPN group， 73 cases) and non diabetic peripheral neuropathy group (NDPN group， 41 cases). The gender， age， duration， body mass index， waist circumference， fasting blood glucose， postprandial blood glucose， glycosylated hemoglobin (HbA1c)， the blood lipid， motor and sensory nerve conduction velocity， carotid intimamedia thickness， foot and ankle brachial index， sensory threshold index were analyzed. Results The age， disease course， fasting and postprandial blood glucose and HbA1c in DPN group were significantly higher than those in NDPN group (P<0.05). The motor and sensory nerve conduction velocity was significantly lower than that in group NDPN (P<0.01)， the carotid intimamedia thickness and foot sensation threshold were significantly higher than those in group NDPN (P<0.05). The data showed that advanced age， long duration and high HbA1c levels in patients with T2DM were independent risk factors of DPN (P<0.05). Conclusion DPN is associated with age， duration and HbA1c level in patients with T2DM.

Key words: diabetes mellitus, type 2；diabetic neuropathies；neural conduction；ankle brachial index

He Ke，Zhu Lihua，Lu Xiwan，Hu Yuan， Zhou Weiqiang， Jiang Yan， Liu Ling， Bian Rongrong. Analysis of related factors of diabetic peripheral neuropathy in patients with type 2 diabetes mellitus[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2018.02.006.

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https://huicui.hebmu.edu.cn/EN/Y2018/V33/I2/115

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Analysis of related factors of diabetic peripheral neuropathy in patients with type 2 diabetes mellitus

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