Abstract: Objective  To investigate the relationship between obstructive  sleep apnea hypopnea syndrome(OSAHS) and blood lipid level in maintenance hemodialysis patients.Methods  A total of 74 patients with maintenance dialysis in our hospital from July 2015 to July2016 were selected as the research objects, and were divided into OSAHS  group (32 cases) and nonOSAHS group (42 cases)in accordance with the monitoring results of the multi sleep monitor.Triglyceride (TG),  total cholesterol (TC), high density lipoprotein (HDLC), low density lipoprotein (LDLC),  apolipoprotein A (ApoA I) and apolipoprotein B (ApoB) were detected and compared between two groups.Logistic regression was used to analyze the influencing factors of OSAHS in maintenance hemodialysis patients.Results  The duration of dialysis in OSAHS group was longer than that in nonOSAHS  group, However, there was no significant difference in BMI between two groups (P>0.05); Two groups of patients with blood lipid levels were compared,  TC,  TG,  LDLC,  ApoB of OSAHS group were significantly higher than in those of nonOSAHS  group (P<0.05); Pearson correlation analysis showed that AHI was positive correlated with TC and ApoB(P＜0.05); Logistic regression analysis showed that ApoB and TC were risk factors for maintenance  hemodialysis patients with OSAHS(P<0.05).Conclusion  The longer the duration of dialysis,  the more risk of OSAHS,  and the synergistic effect of OSAHS presented with dyslipidemia.

Key words: sleep , apnea, , obstructive, renal , dialysis, dyslipidemias