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Choice of vasoactive drugs in sepsis associated acute kidney injur

  

  1. Department of Critical Care Medicine,  the First Affiliated  Hospital of
    Tsinghua University,  Beijing 100016,  China
  • Online:2019-07-20 Published:2019-08-24
  • Contact: Corresponding author: Chao Yangong, Email:chaoyg1059@icloud.com

Abstract: Acute kidney injury (AKI) is closely related to sepsis and is associated with higher hospital mortality. Influencing factors of sepsisrelated AKI include hemodynamic changes, inflammation and direct damage to renal tubular epithelium. In this article, we begin with the epidemiological and pathophysiological mechanisms of sepsisrelated AKI, focusing on the renal hemodynamic changes associated with sepsis, and elaborate on the selection of vasoactive drugs including norepinephrine, epinephrine, vasopressin, dopamine and phenylephrine. It is expected to be helpful to young doctors in related fields.

Key words: acute kidney injury, sepsis