Abstract: Objective  To compare the effects of glycemic management between the National Metabolic Management Center (MMC) and routine hospitalization on patients with type 2 diabetes mellitus(T2DM). Methods  Totally 367 patients with T2DM who were involved in the management of MMC and treated in Ningbo First Hospital's clinic from March, 2018 to January, 2020, were selected as MMC group. The hospitalized patients with T2DM) in Ningbo First Hospital were selected as hospitalization group from March, 2018 to January, 2020 according to 1∶1 matching principle based on age, gender, course, fasting blood grulose's basal level and hemoglobin A1c's basal level. Patients in MMC group were treated according to MMC standards, while those in hospitalization group had routine treatment of threeA hospitals. After the followup of half a year, the effects of two kinds of management on patients glycemic level were analyzed retrospectively.Results  After the followup of half a year, compared with the baseline, fasting blood glucose, hemoglobin A1c, total cholesterol, triglyceride, low density lipoprotein cholesterol, alanine aminotransferase in both groups were significantly improved (P<0.05). Conclusion  MMC has good effects on the improvement of  hemoglobin A1c level which decreased from 8.32% to 6.91% in the patients. Compared with the hospitalization group, MMC group can reach the same level of glucose control.

Key words: diabetes mellitus, , type 2, disease management, hemoglobin A1c