急性肾损伤集束化治疗的研究进展

doi:10.3969/j.issn.1004-583X.2021.04.017

摘要/Abstract

摘要：

急性肾损伤(AKI)是临床常见的急危重症,预后不良。早期识别和尽早规范治疗是改善患者预后的关键。然而临床实践中AKI诊疗差异明显、防治不足等问题突出。近年来,基于改善全球肾脏病预后组织(KDIGO)指南的AKI集束化治疗在临床实践中不断应用发展,特别是与电子预警和新型损伤标志物等早期诊断工具结合,指导AKI早期识别后的规范化治疗,优化了AKI从预警到治疗的管理,有望改善AKI患者预后。

关键词: 急性肾损伤, 集束化治疗, 电子预警, 生物标志物

中图分类号:

R692

陈易欣, 周芳芳, 罗群. 急性肾损伤集束化治疗的研究进展[J]. 临床荟萃, 2021, 36(4): 370-373.

导出引用管理器 EndNote|Ris|BibTeX

链接本文: https://huicui.hebmu.edu.cn/CN/10.3969/j.issn.1004-583X.2021.04.017

https://huicui.hebmu.edu.cn/CN/Y2021/V36/I4/370

参考文献 34

[1]	Hoste EA, Kellum JA, Selby NM, et al. Global epidemiology and outcomes of acute kidney injury[J]. Nat Rev Nephrol, 2018,14(10):607-625. doi: 10.1038/s41581-018-0052-0 pmid: 30135570
[2]	See EJ, Jayasinghe K, Glassford N, et al. Long-term risk of adverse outcomes after acute kidney injury: A systematic review and meta-analysis of cohort studies using consensus definitions of exposure[J]. Kidney Int, 2019,95(1):160-172. doi: 10.1016/j.kint.2018.08.036 URL
[3]	Mehta RL, Cerdá J, Burdmann EA, et al. International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): A human rights case for nephrology[J]. Lancet, 2015,385(9987):2616-2643. doi: 10.1016/S0140-6736(15)60126-X URL
[4]	James MT, Bhatt M, Pannu N, et al. Long-term outcomes of acute kidney injury and strategies for improved care[J]. Nat Rev Nephrol, 2020,16(4):193-205. doi: 10.1038/s41581-019-0247-z URL
[5]	Tang X, Chen D, Yu S, et al. Acute kidney injury burden in different clinical units: Data from nationwide survey in China[J]. PLoS One, 2017,12(2):e0171202. doi: 10.1371/journal.pone.0171202 URL
[6]	Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO clinical practice guideline for acute kidney injury[J]. Kidney Int Suppl, 2012,2:1-138. doi: 10.1038/ki.1972.62 URL
[7]	Hoste EA, Bagshaw SM, Bellomo R, et al. Epidemiology of acute kidney injury in critically ill patients: The multinational AKI-EPI study[J]. Intensive Care Med, 2015,41(8):1411-1423. doi: 10.1007/s00134-015-3934-7 pmid: 26162677
[8]	Yang L, Xing G, Wang L, et al. Acute kidney injury in China: A cross-sectional survey[J]. Lancet, 2015,386(10002):1465-1471. doi: 10.1016/S0140-6736(15)00344-X pmid: 26466051
[9]	Mehta RL, Burdmann EA, Cerdá J, et al. Recognition and management of acute kidney injury in the International Society of Nephrology 0by25 Global Snapshot: A multinational cross-sectional study[J]. Lancet, 2016,387(10032):2017-2025. doi: 10.1016/S0140-6736(16)30240-9 URL
[10]	Meran S, Wonnacott A, Amphlett B, et al. How good are we at managing acute kidney injury in hospital?[J]. Clin Kidney J, 2014,7(2):144-150. doi: 10.1093/ckj/sfu010 pmid: 25852863
[11]	Moore PK, Hsu RK, Liu KD. Management of acute kidney injury: Core curriculum 2018[J]. Am J Kidney Dis, 2018,72(1):136-148. doi: 10.1053/j.ajkd.2017.11.021 URL
[12]	Lavallée JF, Gray TA, Dumville J, et al. The effects of care bundles on patient outcomes: A systematic review and meta-analysis[J]. Implement Sci, 2017,12(1):142. doi: 10.1186/s13012-017-0670-0 URL
[13]	Hoste EA, De Corte W. Implementing the Kidney Disease: Improving Global Outcomes/acute kidney injury guidelines in ICU patients[J]. Curr Opin Crit Care, 2013,19(6):544-553. doi: 10.1097/MCC.0000000000000039 pmid: 24240820
[14]	Forde C, McCaughan J, Leonard N. Acute kidney injury: It's as easy as ABCDE[J]. BMJ Qual Improv Rep, 2012, 1(1): u200370.w200326.
[15]	Tsui A, Rajani C, Doshi R, et al. Improving recognition and management of acute kidney injury[J]. Acute Med, 2014,13(3):108-112.
[16]	Hoste EA, Kashani K, Gibney N, et al. Impact of electronic-alerting of acute kidney injury: Workgroup statements from the 15(th) ADQI Consensus Conference[J]. Can J Kidney Health Dis, 2016,3:10.
[17]	Lachance P, Villeneuve PM, Rewa OG, et al. Association between e-alert implementation for detection of acute kidney injury and outcomes: A systematic review[J]. Nephrol Dial Transplant, 2017,32(2):265-272.
[18]	Wilson FP, Shashaty M, Testani J, et al. Automated, electronic alerts for acute kidney injury: A single-blind, parallel-group, randomised controlled trial[J]. Lancet, 2015,385(9981):1966-1974. doi: 10.1016/S0140-6736(15)60266-5 pmid: 25726515
[19]	Kolhe NV, Staples D, Reilly T, et al. Impact of compliance with a care bundle on acute kidney injury outcomes: A prospective observational study[J]. PLoS One, 2015,10(7):e0132279. doi: 10.1371/journal.pone.0132279 URL
[20]	Kolhe NV, Reilly T, Leung J, et al. A simple care bundle for use in acute kidney injury: A propensity score-matched cohort study[J]. Nephrol Dial Transplant, 2016,31(11):1846-1854. doi: 10.1093/ndt/gfw087 URL
[21]	Chandrasekar T, Sharma A, Tennent L, et al. A whole system approach to improving mortality associated with acute kidney injury[J]. QJM, 2017,110(10):657-666. doi: 10.1093/qjmed/hcx101 pmid: 28521019
[22]	Ebah L, Hanumapura P, Waring D, et al. A multifaceted quality improvement programme to improve acute kidney injury care and outcomes in a large teaching hospital[J]. BMJ Qual Improv Rep, 2017, 6(1): u219176.w217476.
[23]	Selby NM, Casula A, Lamming L, et al. An organizational-level program of intervention for AKI: A pragmatic stepped wedge cluster randomized trial[J]. J Am Soc Nephrol, 2019,30(3):505-515. doi: 10.1681/ASN.2018090886 URL
[24]	Guzzi LM, Bergler T, Binnall B, et al. Clinical use of [TIMP-2]·[IGFBP7] biomarker testing to assess risk of acute kidney injury in critical care: Guidance from an expert panel[J]. Crit Care, 2019,23(1):225. doi: 10.1186/s13054-019-2504-8 URL
[25]	Meersch M, Schmidt C, Hoffmeier A, et al. Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: The PrevAKI randomized controlled trial[J]. Intensive Care Med, 2017,43(11):1551-1561. doi: 10.1007/s00134-016-4670-3 URL
[26]	Göcze I, Jauch D, Götz M, et al. Biomarker-guided intervention to prevent acute kidney injury after major surgery: The prospective randomized BigpAK study[J]. Ann Surg, 2018,267(6):1013-1020. doi: 10.1097/SLA.0000000000002485 URL
[27]	王晶晶, 李竞, 王勇强, 等. 集束化治疗对脓毒症相关性急性肾损伤的影响[J]. 中国急救医学, 2019,39(7):654-658.
[28]	Sykes L, Nipah R, Kalra P, et al. A narrative review of the impact of interventions in acute kidney injury[J]. J Nephrol, 2018,31(4):523-535. doi: 10.1007/s40620-017-0454-2 URL
[29]	Selby NM, Kolhe NV. Care bundles for acute kidney injury: Do they work?[J]. Nephron, 2016,134(3):195-199. doi: 10.1159/000447758 URL
[30]	Tomašev N, Glorot X, Rae JW, et al. A clinically applicable approach to continuous prediction of future acute kidney injury[J]. Nature, 2019,572(7767):116-119. doi: 10.1038/s41586-019-1390-1 pmid: 31367026
[31]	Sarnowski A, Doyle JF, Forni LG. Interventions for improving outcomes in acute kidney injury[J]. Curr Opin Nephrol Hypertens, 2019,28(6):567-572. doi: 10.1097/MNH.0000000000000552 URL
[32]	Logan R, Davey P, Davie A, et al. Care bundles for acute kidney injury: A balanced accounting of the impact of implementation in an acute medical unit[J]. BMJ Open Qual, 2018,7(4):e000392-e000392. doi: 10.1136/bmjoq-2018-000392 URL
[33]	Lamming L, McDonach E, Mohammed MA, et al. Barriers and enablers to the implementation of a complex quality improvement intervention for acute kidney injury: A qualitative evaluation of stakeholder perceptions of the Tackling AKI study[J]. PLoS One, 2019,14(9):e0222444. doi: 10.1371/journal.pone.0222444 URL
[34]	Kashani K, Rosner MH, Haase M, et al. Quality improvement goals for acute kidney injury[J]. Clin J Am Soc Nephrol, 2019,14(6):941-953. doi: 10.2215/CJN.01250119 URL

急性肾损伤集束化治疗的研究进展

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献 34

相关文章 15

编辑推荐

Metrics

本文评价

[1]	马洪珍, 张涛. 生物标志物评估老年慢性肾脏病患者心功能的研究进展[J]. 临床荟萃, 2022, 37(9): 855-859.
[2]	曹晶晶, 张英杰, 常丽娟. 心房颤动发病机制及相关生物标志物研究进展[J]. 临床荟萃, 2022, 37(10): 946-949.
[3]	张琳丽, 麻晓红. 老年髋部骨折术后发生急性肾损伤的临床特点及危险因素分析[J]. 临床荟萃, 2021, 36(5): 442-445.
[4]	孙如梦, 李英. 抗凝相关性肾病研究进展[J]. 临床荟萃, 2020, 35(12): 1148-1152.
[5]	朱然，中国重症超声研究组. 正确应用速尿应激试验[J]. 临床荟萃, 2019, 34(7): 614-616.
[6]	姚玉龙1，李奕然2，武钧3，中国重症超声研究组. 肾脏可复性评估[J]. 临床荟萃, 2019, 34(7): 608-613.
[7]	尹万红，中国重症超声研究组. 液体过负荷与急性肾损伤[J]. 临床荟萃, 2019, 34(7): 604-607.
[8]	晁彦公，中国重症超声研究组. 脓毒症急性肾损伤时血管活性药物的选择[J]. 临床荟萃, 2019, 34(7): 599-603.
[9]	刘丽霞1, 王小亭2, 晁彦公3, 张宏民2, 武钧4，尹万红5, 张丽娜6, 何伟7, 朱然8, 丁欣2, 张倩1, 胡振杰1, 中国重症超声研究组. 脓毒症急性肾损伤：一种微循环疾病[J]. 临床荟萃, 2019, 34(7): 595-598.
[10]	胡成欢，张丽娜，中国重症超声研究组. 肾脏灌注压多少合适？[J]. 临床荟萃, 2019, 34(7): 590-594.
[11]	郝晓萍，邬碧波，张黎明，俞华，唐琦. 尿肝型脂肪酸结合蛋白对急性失代偿性心力衰竭患者发生急性肾损伤的预测[J]. 临床荟萃, 2019, 34(4): 326-329.
[12]	刘华杰1，高霞2. 新生儿早期肾损伤的评估：经典指标到代谢组学的革新[J]. 临床荟萃, 2018, 33(9): 825-828.
[13]	胡志伟. 86例急性肾损伤患者的临床特征及分析[J]. 临床荟萃, 2018, 33(2): 150-152.
[14]	曹琦琪1，黄军悦2，谌卫3，张懿3，郭志勇3. RIFLE标准在肾科会诊术后急性肾损伤中的应用[J]. 临床荟萃, 2017, 32(10): 861-864.
[15]	张瑶1，田祥2，耿巍2，张旗2，甄利波2，刘倩梅2，杨颖2，宋达2. 胱抑素C对对比剂肾病的预测价值[J]. 临床荟萃, 2016, 31(7): 770-773,778.